Competence center 2D & 3D printing technology

We offer following services in printed drug formulations

  • Development of sophisticated formulation concepts using printing techniques
  • Conduct of feasibility studies (proof of concept) for new molecular entities
  • Filament and ink formulations
  • Dose-finding studies using 2D printing
  • Lifecycle management
  • Effective network with equipment providers, specialized raw material suppliers and universities

All services are also available for formulations containing high-potent drugs & narcotics and under GMP requirements.

Advantages of printed drug formulation

  • Individually manufactured
  • Individual doses
  • Small batch sizes or single drug batch size possible
  • Tailored release characteristics
  • Fast on-set
  • Combination of APIs not compatible with conventional manufacturing techniques
  • Combination of APIs that are not marketed
  • Improvement of drug product stability

Innovative, cost-effective, individualized dosage forms, small batch sizes –
all possible @ Gen-Plus with the 2D and 3D API printing technology

Personalized medicine

  • Tailor-made pharmacotherapies
  • With respect to individual health situation
  • Considering physiological constitution
  • Genetic, metabolic and gender-specific characteristics

Solid Dosage Forms

For the preparation of solid dosage forms we use various technologies. This enables us to meet the particular requirements of the targeted product, e.g. Immediate Release (IR), Modified Release (MR), Controlled Release (CR), Extended Release (ER) / Sustained Release (SR).

A substantial number of products have been successfully developed:

  • Tablets (Mono- / Multi-layer Tablets, Effervescent Tablets)
  • Film Tablets
  • Orodispersible Tablets (sublingual Tablets, super-fast dissolving Tablets)
  • Capsules
  • Granulates
  • Pellets
  • Adsorbates
  • Lyophilisates

Manufacturing technologies at Gen-Plus include:

  • Fluidized bed granulation
  • Compaction
  • Coating
  • Fluidized bed drying
  • Hot melt granulation
  • Tray drying
  • Single pot granulation
  • Sieving
  • Diffusion blending
  • Forced blending
  • Grinding
  • Spray drying
  • Tableting
  • Capsule filling

Semi-solid Dosage Forms

In the area of semi-solid dosage forms we offer services like feasibility studies and permeation experiments through human skin, as well as stability studies under ICH conditions.

Patches / Oral Thin Films

In the field of transdermal drug delivery systems (TDS) and oral thin films (ODF) we offer development service in the range of small-scale samples up to the manufacturing of phase I clinical samples. We are equipped with a pilot machine for continuous coating, a cutting machine and a punching/packing machine with an output of 25 units / min.

HME – Hot Melt Extrusion

With Hot Melt Extrusion (HME) we offer a continuous production process, which allows improving the bioavailability of challenging APIs (BCS class III and IV).

Micro-/ Nanoemulsions

We offer the development of Micro-/Nanoemulsions and their incorporation in solid dosage forms. These technologies enable the solubilisation of poorly soluble APIs, resulting in an improved bioavailability.

Amorphization of APIs

We offer a wide range of technologies for amorphization like:

  • Hot Melt Extrusion
  • Spray drying / Embedding
  • Freeze-drying
  • Precipitation / Co-Precipitation
  • Adsorption on the surface of (mesoporous) materials

High Containment Technologies

Our well-established high containment technology enables us to offer feasibility studies with highly effective/highly toxic substances (OEB classes 4/5).

Equipment for all kind of oral solid manufacturing is available in high containment cabinets.

New Technologies

Gen-Plus is continuously engaged in getting access to innovative pharmaceutical technologies:

PLEASE-Technology is based on controlled on laser perforation of the skin (epidermal stratum corneum), which allows a facilitated transport of topical peptide formulations through the skin.

Using 2D & 3D-Printing-Technology we aim for the development of personalized solid dosage forms regarding dosage and release

More Information?

Together with our business partners, we develop innovative formulation concepts and new technologies.

+49 89-780179-40

Our Solutions

Our technologies at Gen-Plus include:

Original Products /

We formulate new drug products and hard-to-formulate active ingredients.

Generica /

We manufacture for you medicinal products for Phase I studies.

Biotech /

In cooperation with manufacturers of APIs from the Biotech field, we pursue the development of innovative formulations.


In the field of contract development, we offer feasibility studies and check your API, to find out how to make best use of it to meet your goal.

IMP Manufacturing

We are a certified manufacturer for clinical samples Phase I, for Phase I studies. We are currently focused on oral solids.


An important issue in pharmaceutical development is the protection of intellectual property through patents.


Permeation, dissolution and particle characterization.


Full range of services for narcotic substances and products.

Consulting and Compliance

Pharmaceutical consulting services


Please use the contact details or form below.

Tel. +49 89-780179-40